Common Cancer Biomarkers

cancer biomarkers

MicroRNAs as biomarkers associated with bladder cancer

Bladder cancer is the fifth most common cancer with significant morbidity and mortality. Recently, numerous studies demonstrated that microRNAs are emerging as diagnostic biomarkers for bladder cancer. Specific miRNA profiles have been identified for several samples from patients with bladder cancer. MicroRNAs are noncoding RNA molecules of approximately 23 nucleotides that play important roles...

Role of Molecular Biomarkers in Colorectal Cancer

Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...

Predictive Biomarkers and Personalized Medicine Common Cancer Stem Cell Gene Variants Predict Colon Cancer Recurrence

Purpose: Recent evidence suggests that cancer stem cells (CSC) are responsible for key elements of colon cancer progression and recurrence. Germline variants in CSC genes may result in altered gene function and/or activity, thereby causing interindividual differences in a patient’s tumor recurrence capacity and chemoresistance. We investigated germline polymorphisms in a comprehensive panel of ...

Cancer epidemiology, biomarkers & prevention, and cancer prevention research: two journals, a common goal.

Prevention and control are key components of cancer research and the effort to reduce cancer incidence and mortality. The National Cancer Policy Board of the Institute of Medicine and National Research Council (1) stated that a national strategy for cancer prevention and control (CPC) should be a central focus of cancer research. The American Association for Cancer Research (AACR) and other nat...